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  • Observational Study
    In person & Online

    What is this Study about?

    This study will assess if an in-vehicle Driving Monitoring System can identify differences in driving behaviours between older adults who are cognitively healthy, those with mild cognitive impairment, and those with mild dementia. 

    Eligibility Criteria

    Participants must:

    • Be 65 years or older.

    • Be cognitively healthy or have mild cognitive impairment or mild dementia.

    • Have a valid General class driver’s license and still driving.

    • Be fluent in English.

    • Own an insured vehicle of 1998 or newer model year.

    • Drive to at least 2 different locations per week. 

    Recruitment End Date

  • Observational Study
    In person

    What is this Study about?

    This study explores Deep Brain Stimulation (DBS) as a potential treatment for mild Alzheimer’s disease (AD). In this study, the mild electrical stimulation is delivered to a part of the brain called the Pedunculopontine Nucleus (PPN), which helps regulate cognitive and sleep-related brain rhythms. The trial will recruit a small group of participants to evaluate the safety, feasibility, and preliminary efficacy of DBS-PPN in treating AD. The goal of this study is to see if targeting this part of the brain with DBS can help people living with mild AD improve their memory, thinking skills, and sleep quality.

    Eligibility Criteria

    Are 60 years or older
    -Have a diagnosis of mild Alzheimer's Disease
    -Are fluent in English
    -Have a personal caregiver willing to join the study

    Recruitment End Date

  • Observational Study
    In person and online

    What is this Study about?

    Many older adults start to experience poorer sleep quality as they age, which can be associated with worse memory and cognition. Previous studies have shown that sleep can be improved when quiet sounds are presented at the right times during slow-wave sleep. We are interested in whether we can improve sleep and associated memory and cognitive function using these sounds in older adults. Information gathered from this study will be used to inform whether quiet sounds presented during slow-wave sleep can improve sleep, memory, and cognitive function.

    Eligibility Criteria

    Are 60 and older with and without mild cognitive impairment (MCI) You must be able to read, speak, or understand English.

     If you do not have:

    1) major psychiatric or neurological disorders

    2) moderate to severe depressive or anxiety symptoms

    (3) sleep disorders

    (4) serious medical illness

    (5) known stroke or transient ischemic attack

    (6) alcohol or substance abuse

    (7) a history of seizures

    (8) chronic use of psychoactive or hypnotic medications, or use of any medication that alters sleep

    (9) significant hearing loss or hearing aid use

    (10) untreated moderate or severe sleep apnea on a home sleep apnea test.

    Participants with well-controlled sleep apnea will be eligible to participate provided they are able to use their CPAP machine or other treatment device throughout the study

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    Thinking skills (also known as cognitive functions), change from younger to older adulthood. In this study we are investigating how these shifting architectures of cognition and brain function relate to one another, and how these brain and cognitive changes impact decision-making in younger and older adults.

    You may qualify to participate if you are: 1) 60 years of age or older, 2) right-handed, 3) in good health, 4) and have normal or corrected-to-normal vision. Participation will involve completing cognitive tasks, questionnaires, and non-invasive brain measurements using MRI. If you are interested in participating in this study, please contact [email protected]

    Eligibility Criteria

    You are eligible to participate if you:

    - Are aged 60 years or older

    - Are right-handed

    - Are cognitively healthy

    - Are able to come in-person to our site, located at the Montreal Neurological Institute

    - Have no metal in your body (e.g., pacemaker, metal plates, orthopedic devices, etc.)

    - Speak English or French

    Recruitment End Date

  • Observational Study
    In person and online

    What is this Study about?

    This research aims to explore the perspectives of older adults living with dementia, providing a nuanced understanding of their experiences and challenges. Second, it seeks to investigate the role of physical activities in their lives, examining how engagement in such activities influences their cognitive function and mental well-being. Finally, this research aims to inform interventions and policies that can support older adults in maintaining their cognitive health and overall well-being.


    The data will be used for the researcher’s master’s thesis, and for publishing peer-reviewed and non-peer reviewed articles, conference presentations, webinars, and presentations for professionals.

    Eligibility Criteria

    1.You are eligible to participate if you are a member of the Minds in Motion program.
    2.You are eligible to participate if you age 65 and above.
    3.You are eligible to participate if you are diagnosed with mild-to-moderate dementia.
    4.You are eligible to participate if you actively engaged in some form of physical activity in addition to minds in motion physical activities (e.g. swimming, nature walks, aerobics, chair exercises).
    5. You are eligible to participate if you can give informed consent.

    Recruitment End Date

  • Observational Study
    In person and online

    What is this Study about?

    This study aims to evaluate the acceptance and usability of the GuardIO Family Care app, a mobile application designed to support community safety for individuals living with dementia or mild cognitive impairment and their care partners. The study also aims to analyze mobility patterns collected from the app to explore how mobility data can contribute to the early detection of cognitive impairment. The findings will help improve app design, inform care strategies, and support early intervention efforts for individuals living with dementia or MCI.

    Eligibility Criteria

    You are eligible to participate if you:

    Are 18 years of age or older

    Are living with mild cognitive impairment (MCI) or dementia, or are a care partner of someone with MCI or dementia

    Are able to use a smartphone or tablet with the GuardIO app

    Are willing to participate in the study activities, including using the app, completing questionnaires, and attending an optional focus group

    Can understand and communicate in English (or another supported language, if applicable)

    Recruitment End Date

  • Observational Study
    In-Person

    What is this Study about?

    The study involves a primary session of paper-and-pencil tasks, and a second session of a computer task, while your heart rate and brain activity is monitored. The aim of the study is to examine how signals are affected from the body to the brain.

    Eligibility Criteria

    - You are between the ages of 18-30 or 60-85

    - Free from conditions (other than amnestic mild cognitive impairment (aMCI)) which affect cognition or cardiac health

    - Fluent in the English language

    - Have normal or corrected-to-normal vision

    Recruitment End Date

  • Observational Study
    Online & In-Person

    What is this Study about?

    In collaboration with our South Asian community collaborators, our goal is to gain an in-depth understanding of new immigrant, multigenerational, South Asian family caregiving for a relative with dementia amidst COVID-19. The goal is to inform future family-centered, healthcare interventions aimed at supporting equity deserving families during times of crisis.

    To achieve our goal, we are starting to recruit family care partners living in a multigenerational home and caring for a relative with dementia from each of the four groups of South Asian families. We will be using a multiple case study to examine new immigrant, multigenerational caregiving for a relative with dementia from the perspective of four groups of South Asian families; 1) Pakistani, 2) Bangladeshi, 3) Indian, and 4) Sri Lankan. We will also be using secondary data sources, including genograms, ecoMaps, and key documents.

    We will be conducting interviews with a family care partners from each of the four groups. Following these interviews, we will hold four focus groups with a new purposeful sample of South Asian multigenerational care partners to understand if the findings from the interviews reflect their caregiving experiences thereby increasing the reliability of the study findings.

    Eligibility Criteria

    You are eligible if

    1. You are caring for a family member or relative with memory loss or dementia

    2. You are living in a multigenerational South Asian Family

    3. You Identify with any of these four South Asian Countries: India, Pakistan, Bangladesh and Sri Lanka

    4. You live in the Greater Toronto Area (GTA)

    Recruitment End Date

  • Observational Study
    Online & In-Person

    What is this Study about?

    The aim of this study is to develop a large, ethically sources, and diverse database of voice recordings to determine whether voice has biomarkers for particular disease categories, including neurological and neurodevelopmental conditions. The data that is collected will be used to develop a full open-access database to fuel artificial intelligence research related to voice.

    Eligibility Criteria

    • Between ages of 44-85
    • Able to read, write, speak, and understand English
    • Be diagnosed with one of the following conditions:
      • Alzheimer’s disease
      • Parkinson’s disease
      • Amyotrophic Lateral Sclerosis
      • Mild Cognitive Impairment, or other types of dementia
    • Consent to provide a voice/speech sample

    Recruitment End Date